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ST3GAL6 Antikörper (C-Term)

ST3GAL6 Reaktivität: Human, Maus, Ratte WB, EIA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500813
  • Target Alle ST3GAL6 Antikörper anzeigen
    ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
    Bindungsspezifität
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 2
    Kaninchen
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Dieser ST3GAL6 Antikörper ist unkonjugiert
    Applikation
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
    Spezifität
    This antibody detects ST3GAL6.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse and Rat
    Aufreinigung
    Peptide Affinity Chromatography
    Immunogen
    ST3gal6 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human ST3gal6.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
    Andere Bezeichnung
    ST3GAL6 (ST3GAL6 Produkte)
    Synonyme
    SIAT10 antikoerper, ST3GALVI antikoerper, 1700023B24Rik antikoerper, AI930218 antikoerper, AW552396 antikoerper, Siat10 antikoerper, St3galVI antikoerper, ST3GAL-VI antikoerper, ST3 beta-galactoside alpha-2,3-sialyltransferase 6 antikoerper, ST3GAL6 antikoerper, St3gal6 antikoerper
    Hintergrund
    Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.Synonyms: 3-sialyltransferase, 3-sialyltransferase VI, CMP-NeuAc:beta-galactoside alpha-2, SIAT10, ST3Gal VI, ST3GalVI, Sialyltransferase 10, Type 2 lactosamine alpha-2
    Gen-ID
    10402
    NCBI Accession
    NP_006091
    Pathways
    Glycosaminoglycan Metabolic Process
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