ST3GAL6 Antikörper (C-Term)

Produktnummer ABIN500813

Der Kaninchen Polyklonal Anti-ST3GAL6-Antikörper wurde für WB, EIA und IF validiert. Er ist geeignet, ST3GAL6 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ST3GAL6 Antikörper (C-Term) (ABIN500813)

Target: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST3GAL6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Produktdetails anti-ST3GAL6 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects ST3GAL6.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat

Aufreinigung: Peptide Affinity Chromatography

Immunogen: ST3gal6 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human ST3gal6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ST3GAL6

Target: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Andere Bezeichnung: ST3GAL6

Hintergrund: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.Synonyms: 3-sialyltransferase, 3-sialyltransferase VI, CMP-NeuAc:beta-galactoside alpha-2, SIAT10, ST3Gal VI, ST3GalVI, Sialyltransferase 10, Type 2 lactosamine alpha-2

Gen-ID: 10402

NCBI Accession: NP_006091

Pathways: Glycosaminoglycan Metabolic Process