IL1RL1 Antikörper (N-Term)

Produktnummer ABIN500811

Dieses Anti-IL1RL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL1RL1 in WB, IHC (p) und EIA. Geeignet für Human und Maus.

Kurzübersicht für IL1RL1 Antikörper (N-Term) (ABIN500811)

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1RL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-IL1RL1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects ST2 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Peptide Affinity Chromatography

Immunogen: A synthetic peptide corresponding to 16 amino acids at the amino-terminus of Mouse ST2. Remarks: This peptide is common to all three known ST2 isoforms.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Positive Control: Mouse Kidney Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL1RL1

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Andere Bezeichnung: IL1RL1 / ST2

Hintergrund: ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF (3). More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance (4,5). It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP (6).Synonyms: DER4, FIT-1, Homolog of mouse growth stimulation-expressed, Interleukin-1 receptor-like 1, MGC32623

Gen-ID: 9173

NCBI Accession: NP_003847