Olfactomedin 3 Antikörper (AA 101-200) (AbBy Fluor® 750)

Produktnummer ABIN5008008

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Olfactomedin 3 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für Olfactomedin 3 Antikörper (AA 101-200) (AbBy Fluor® 750) (ABIN5008008)

Target: Olfactomedin 3 (OLFM3)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Olfactomedin 3 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Olfactomedin 3 Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OLFM3/Optimedin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Olfactomedin 3

Target: Olfactomedin 3 (OLFM3)

Andere Bezeichnung: OLFM3/Optimedin

Hintergrund:

Synonyms: Noe3, NOE3_HUMAN, Noelin 3, Noelin-3, NOELIN3, NOELIN3 V1, NOELIN3 V2, NOELIN3 V3, NOELIN3 V4, NOELIN3 V5, NOELIN3 V6, Olfactomedin 3, Olfactomedin related ER localized protein 3, Olfactomedin-3, Olfactomedin3, Olfm3, Optimedin.

Background: OLFM3 is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.