Reticulon 4 Antikörper (AA 301-400) (AbBy Fluor® 750)
Kurzübersicht für Reticulon 4 Antikörper (AA 301-400) (AbBy Fluor® 750) (ABIN5007767)
Target
Alle Reticulon 4 (RTN4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-400
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Kreuzreaktivität
- Human, Ratte
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Homologie
- Mouse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse RTN4 protein
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Isotyp
- IgG
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Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Reticulon 4 (RTN4)
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Andere Bezeichnung
- Nogo-A
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Hintergrund
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Synonyms: ASY, NgA, NOGO, NSP-CL, Nogo-A, Nogo-B, Nogo-C, AA407876, AA409940, AA960376, mKIAA0886, mKIAA4153, 1110020G17Rik, C130026I10Rik, Reticulon-4, Neurite outgrowth inhibitor, Nogo protein, Rtn4, Kiaa0886
Background: Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing.
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Gen-ID
- 68585
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UniProt
- Q99P72
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Pathways
- Neurotrophin Signalübertragung, Regulation of Cell Size, SARS-CoV-2 Protein Interaktom
Target
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