SLITRK2 Antikörper (Middle Region)

Produktnummer ABIN500756

Der Kaninchen Polyklonal Anti-SLITRK2-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, SLITRK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SLITRK2 Antikörper (Middle Region) (ABIN500756)

Target: SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLITRK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-SLITRK2 Antikörper

Bindungsspezifität: Middle Region

Spezifität: This antibody detects SLITRK2 at center. It is predicted to have no cross-reactivity to other Slitrk proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: Slitrk2 antibody was raised against a 16 amino acid peptide from near the center of human Slitrk2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu SLITRK2

Target: SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))

Andere Bezeichnung: SLITRK2

Hintergrund: SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.Synonyms: CXorf2, KIAA1854, SLIT and NTRK-like protein 2, SLITL1

Gen-ID: 84631

UniProt: Q9H156