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SLITRK1 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-SLITRK1-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, SLITRK1 in Proben von Ratte, Human und Maus zu detektieren.
Produktnummer ABIN500750

Kurzübersicht für SLITRK1 Antikörper (C-Term) (ABIN500750)

Target

Alle SLITRK1 Antikörper anzeigen
SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Reaktivität

  • 22
  • 11
  • 9
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Ratte, Human, Maus

Wirt

  • 26
  • 1
Kaninchen

Klonalität

  • 27
Polyklonal

Konjugat

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SLITRK1 Antikörper ist unkonjugiert

Applikation

  • 14
  • 13
  • 10
  • 7
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody detects SLITRK1 at C-term. It is predicted to have no cross-reactivity to other Slitrk proteins.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Huamn, mouse, rat

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    Slitrk1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Slitrk1.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target

    SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

    Andere Bezeichnung

    SLITRK1

    Hintergrund

    SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.Synonyms: KIAA1910, LRRC12, Leucine-rich repeat-containing protein 12, SLIT and NTRK-like protein 1

    Gen-ID

    114798

    NCBI Accession

    NP_443142

    UniProt

    Q96PX8
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