NDRG1 Antikörper (pThr346) (AbBy Fluor® 680)

Produktnummer ABIN5007342

Produktdetails anti-NDRG1 Antikörper (AbBy Fluor® 680)

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Bindungsspezifität: pThr346

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDRG1 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human NDRG1 around the phosphorylation site of Thr346

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Andere Bezeichnung: NDRG1 (NDRG1 Produkte)

Hintergrund:

Synonyms: N-myc downstream regulated gene 1, TDD5, 42 kDa, cap43, cmt4d, Dferentiation related gene1 protein, Drg 1, drg1, gc4, hmsnl, Human mRNA for RTP complete cds, N myc downstream regulated gene 1 protein, Ndr 1, NDRG 1, Nickel specic induction protein Cap43, Nmyc downstream regulated gene1, Protein NDRG1, Protein regulated by oxygen 1 , Protein regulated by oxygen1, proxy1, reducin, Reducing agents and tunicamycin responsive protein, rit42, rtp, targ1, tdds, tunicamycin-responsive protein.

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. May have a growth inhibitory role. Ubiquitous, expressed most prominently in placental membranes and prostate, kidney, small intestine, and ovary tissues. Reduced expression in adenocarcinomas compared to normal tissues. In colon, prostate and placental membranes, the cells that border the lumen show the highest expression.

Gen-ID: 10397