SIPA1L3 Antikörper (N-Term)

Produktnummer ABIN500720

Der Kaninchen Polyklonal anti-SIPA1L3 Antikörper wird verwendet zum Nachweis von SIPA1L3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für SIPA1L3 Antikörper (N-Term) (ABIN500720)

Target: SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIPA1L3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-SIPA1L3 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: SIPA1L3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human SIPA1L3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu SIPA1L3

Target: SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

Andere Bezeichnung: SIPA1L3

Hintergrund: Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice (3) and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.Synonyms: KIAA0545, SPA-1-like protein 3, SPAL3, Signal-induced proliferation-associated 1-like protein 3

Gen-ID: 23094

NCBI Accession: NP_055888

UniProt: O60292