Membralin Antikörper (AA 161-260) (AbBy Fluor® 750)

Produktnummer ABIN5006765

Dieses Anti-Membralin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Membralin in WB, IF (cc) und IF (p). Geeignet für Zebrafisch (Danio rerio).

Kurzübersicht für Membralin Antikörper (AA 161-260) (AbBy Fluor® 750) (ABIN5006765)

Target: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Membralin Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Membralin Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 161-260

Kreuzreaktivität: Zebrafisch (Danio rerio)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Membralin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Membralin

Target: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Andere Bezeichnung: Membralin/C19orf6

Hintergrund:

Synonyms: ASBABP1, C19orf6, MGC4022, R32184_3, aspecic BCL2 ARE-binding protein 1, C19orf6, chromosome 19 open reading frame 6, MBRL, MBRL_HUMAN.

Background: The gene encoding human Membralin, C19orf6, localizes to chromosome 19p13.3. It contains 11 exons, which encode at least two splice variants in human cancer. Membralin is a multi-pass membrane protein and exists either as a long or short form. The long form of Membralin comprises all 11 exons, while the short form contains all exons except exon 10. Expression of different Membralin isoforms depends on tissue type. The long form is expressed in ovarian and colorectal carcinomas, whereas the short form is expressed in breast or pancreatic carcinomas. Because Membralin expression in ovarian carcinomas is highest in serous carcinomas as compared to surface epithelium carcinomas, expression of Membralin may be useful as a novel tumor-associated marker in ovarian serous carcinomas.