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Membralin Antikörper (AA 161-260) (AbBy Fluor® 750)

Dieses Anti-Membralin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Membralin in WB, IF (cc) und IF (p). Geeignet für Zebrafisch (Danio rerio).
Produktnummer ABIN5006765

Kurzübersicht für Membralin Antikörper (AA 161-260) (AbBy Fluor® 750) (ABIN5006765)

Target

Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Reaktivität

  • 16
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Zebrafisch (Danio rerio)

Wirt

  • 21
Kaninchen

Klonalität

  • 21
Polyklonal

Konjugat

  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Membralin Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation

  • 21
  • 12
  • 12
  • 5
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 2
    • 1
    • 1
    AA 161-260

    Kreuzreaktivität

    Zebrafisch (Danio rerio)

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Membralin

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

    Andere Bezeichnung

    Membralin/C19orf6

    Hintergrund

    Synonyms: ASBABP1, C19orf6, MGC4022, R32184_3, aspecic BCL2 ARE-binding protein 1, C19orf6, chromosome 19 open reading frame 6, MBRL, MBRL_HUMAN.

    Background: The gene encoding human Membralin, C19orf6, localizes to chromosome 19p13.3. It contains 11 exons, which encode at least two splice variants in human cancer. Membralin is a multi-pass membrane protein and exists either as a long or short form. The long form of Membralin comprises all 11 exons, while the short form contains all exons except exon 10. Expression of different Membralin isoforms depends on tissue type. The long form is expressed in ovarian and colorectal carcinomas, whereas the short form is expressed in breast or pancreatic carcinomas. Because Membralin expression in ovarian carcinomas is highest in serous carcinomas as compared to surface epithelium carcinomas, expression of Membralin may be useful as a novel tumor-associated marker in ovarian serous carcinomas.

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