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DDIT4 Antikörper (N-Term)
DDIT4
Reaktivität: Human, Ratte, Maus
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-DDIT4 Antikörper
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Target
Alle DDIT4 Antikörper anzeigen
DDIT4
(DNA-Damage-Inducible Transcript 4 (DDIT4))
Bindungsspezifität
Alle Epitope für DDIT4 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für DDIT4 Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für DDIT4 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für DDIT4 Antikörper
Polyklonal
Konjugat
Alle Konjugate für DDIT4 Antikörper
Dieser DDIT4 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für DDIT4 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody detects DDIT4 at N-term.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Peptide affinity chromatography
Immunogen
RTP801 antibody was raised against a 14 amino acid peptide from near the amino terminus of human DDIT4.
Isotyp
IgG
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Discover our top product DDIT4 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
ELISA. Western blot: 2 - 4 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu DDIT4
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Target
DDIT4
(DNA-Damage-Inducible Transcript 4 (DDIT4))
Andere Bezeichnung
DDIT4 (DDIT4 Produkte )
Synonyme
redd1 antikoerper, Dig2 antikoerper, REDD-1 antikoerper, REDD1 antikoerper, 5830413E08Rik antikoerper, AA415483 antikoerper, Rtp801 antikoerper, dig2 antikoerper, rtp801 antikoerper, sb:cb821 antikoerper, zgc:64114 antikoerper, DNA damage inducible transcript 4 antikoerper, DNA-damage-inducible transcript 4 antikoerper, DNA damage inducible transcript 4 S homeolog antikoerper, ddit4 antikoerper, DDIT4 antikoerper, Ddit4 antikoerper, ddit4.S antikoerper
Hintergrund
RTP801 was initially identified as a gene induced by DNA damage, and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment. Recently, RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle. In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. Disregulation of RTP801 may thus contribute to human tumorigenesis.Synonyms: DDIT-4, DNA-damage-inducible transcript 4, Dig2, HIF-1 responsive protein, Protein regulated in development and DNA damage response 1, REDD-1, REDD1, RTP801
Gen-ID
54541
NCBI Accession
NP_061931
UniProt
Q9NX09
Pathways
Neurotrophin Signalübertragung , Regulation of Carbohydrate Metabolic Process
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