RPAIN Antikörper (C-Term)
Kurzübersicht für RPAIN Antikörper (C-Term) (ABIN500632)
Target
Alle RPAIN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody detects RPA Interacting Protein at C-term.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
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Aufreinigung
- Peptide affinity chromatography
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Immunogen
- RPA IP antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human RPA IP.
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Isotyp
- IgG
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Applikationshinweise
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ELISA. Wester blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- RPAIN (RPA Interacting Protein (RPAIN))
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Andere Bezeichnung
- RPAIN / RIP
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Hintergrund
- Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.Synonyms: RPA-interacting protein
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Gen-ID
- 84268
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NCBI Accession
- NP_001028174
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UniProt
- Q86UA6
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Pathways
- Protein targeting to Nucleus
Target
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