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MEX3A Antikörper (C-Term)

MEX3A Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500620
  • Target Alle MEX3A Antikörper anzeigen
    MEX3A (Mex-3 Homolog A (MEX3A))
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 7
    Kaninchen
    Klonalität
    • 7
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    Dieser MEX3A Antikörper ist unkonjugiert
    Applikation
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Rkhd4.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    Rkhd4 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Rkhd4.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    MEX3A (Mex-3 Homolog A (MEX3A))
    Andere Bezeichnung
    MEX3A / RKHD4 (MEX3A Produkte)
    Synonyme
    RKHD4 antikoerper, MEX-3A antikoerper, 2700083E18Rik antikoerper, Gm411 antikoerper, Rkhd4 antikoerper, mex-3 RNA binding family member A antikoerper, mex-3 RNA binding family member A L homeolog antikoerper, mex3 RNA binding family member A antikoerper, MEX3A antikoerper, mex3a.L antikoerper, Mex3a antikoerper
    Hintergrund
    Rkhd4, also known as MEX3A is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd4, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. While Rkhd2 has been suggested to be associated with susceptibility to essential hypertension type 8, the function of Rkhd4 remains unknown. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: RING finger and KH domain-containing protein 4, RNA-binding protein MEX3A
    Gen-ID
    92312
    UniProt
    A1L020
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