RANBP10 Antikörper (Center)

Produktnummer ABIN500565

Dieses Anti-RANBP10-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RANBP10 in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für RANBP10 Antikörper (Center) (ABIN500565)

Target: RANBP10 (RAN Binding Protein 10 (RANBP10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANBP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-RANBP10 Antikörper

Bindungsspezifität: Center

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Peptide affinity chromatography

Immunogen: RANBP10 antibody was raised against a 15 amino acid peptide near the center of human RANBP10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RANBP10

Target: RANBP10 (RAN Binding Protein 10 (RANBP10))

Andere Bezeichnung: RANBP10

Hintergrund: The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.Synonyms: KIAA1464, Ran-binding protein 10

Gen-ID: 57610

UniProt: Q6VN20