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PRTFDC1 Antikörper (Center)
PRTFDC1
Reaktivität: Human, Ratte, Maus
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-PRTFDC1 Antikörper
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Target
Alle PRTFDC1 Antikörper anzeigen
PRTFDC1
(phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
Bindungsspezifität
Alle Epitope für PRTFDC1 Antikörper
Center
Reaktivität
Alle Reaktivitäten für PRTFDC1 Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für PRTFDC1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PRTFDC1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PRTFDC1 Antikörper
Dieser PRTFDC1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PRTFDC1 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody detects PRTFDC1.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Peptide affinity chromatography
Immunogen
PRTFDC1 antibody was raised against a 14 amino acid peptide from near the center of human PRTFDC1.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
ELISA. Western blot: 0.5 - 1 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu PRTFDC1
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Target
PRTFDC1
(phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
Andere Bezeichnung
PRTFDC1 (PRTFDC1 Produkte )
Synonyme
HHGP antikoerper, HPRT antikoerper, hprt1 antikoerper, hprt1l antikoerper, zgc:55561 antikoerper, zgc:86771 antikoerper, MGC80959 antikoerper, OTTMUSG00000011667 antikoerper, Prtfdc1 antikoerper, phosphoribosyl transferase domain containing 1 antikoerper, phosphoribosyl transferase domain containing 1 L homeolog antikoerper, phosphoribosyltransferase domain containing 1 pseudogene antikoerper, PRTFDC1 antikoerper, prtfdc1 antikoerper, Prtfdc1 antikoerper, prtfdc1.L antikoerper, Gm13377 antikoerper
Hintergrund
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.Synonyms: HHGP, Phosphoribosyltransferase domain-containing protein 1
Gen-ID
56952
NCBI Accession
NP_064585
UniProt
Q9NRG1
Pathways
Ribonucleoside Biosynthetic Process
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