PLXDC2 Antikörper (C-Term)

Produktnummer ABIN500517

Dieses Anti-PLXDC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PLXDC2 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PLXDC2 Antikörper (C-Term) (ABIN500517)

Target: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLXDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PLXDC2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Plxdc2 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: Plxdc2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human Plxdc2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu PLXDC2

Target: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Andere Bezeichnung: PLXDC2 / TEM7R

Hintergrund: Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57 % amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.Synonyms: Plexin domain-containing protein 2, Tumor endothelial marker 7-related protein

Gen-ID: 84898

UniProt: Q6UX71