Homeobox C5 Antikörper (AA 151-222) (AbBy Fluor® 750)

Produktnummer ABIN5004823

Der Kaninchen Polyklonal Anti-Homeobox C5-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, Homeobox C5 in Proben von Human und Maus zu detektieren.

Kurzübersicht für Homeobox C5 Antikörper (AA 151-222) (AbBy Fluor® 750) (ABIN5004823)

Target: Homeobox C5 (HOXC5)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Homeobox C5 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Homeobox C5 Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 151-222

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXC5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Homeobox C5

Target: Homeobox C5 (HOXC5)

Andere Bezeichnung: HOXC5

Hintergrund:

Synonyms: CP11, homeo box C5, homeobox C5, Homeobox protein CP11, homeobox protein Hox C5, Homeobox protein Hox-3D, Homeobox protein Hox-C5, Hox 3D, HOX3, HOX3D, HOXC5, HXC5_HUMAN, OTTHUMP00000217386.

Background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxC5 is a 222 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Existing as multiple alternatively spliced isoforms, HoxC5 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. The gene encoding HoxC5 maps to a cluster of Hox proteins on chromosome 12 that are essential for morphogenesis. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.