4932442K08Rik antikoerper, AW049283 antikoerper, AW413338 antikoerper, CCPG antikoerper, Pgcc1 antikoerper, mKIAA1838 antikoerper, KIAA1838 antikoerper, PGCC1 antikoerper, dJ894D12.1 antikoerper, RGD1310304 antikoerper, family with sequence similarity 120B antikoerper, family with sequence similarity 120, member B antikoerper, FAM120B antikoerper, Fam120b antikoerper
Hintergrund
The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.Synonyms: CCPG, Constitutive coactivator of PPAR-gamma, Constitutive coactivator of PPARG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, FAM120B, KIAA1838, PGCC1, PPARG constitutive coactivator 1, Protein FAM120B