Der Kaninchen Polyklonal Anti-FAM120B-Antikörper wurde für WB und EIA validiert. Er ist geeignet, FAM120B in Proben von Human, Maus und Ratte zu detektieren.
FAM120B
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 488
Applikationshinweise
ELISA. Western blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target
FAM120B
(Family with Sequence Similarity 120B (FAM120B))
Andere Bezeichnung
FAM120B
Hintergrund
The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.Synonyms: CCPG, Constitutive coactivator of PPAR-gamma, Constitutive coactivator of PPARG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, FAM120B, KIAA1838, PGCC1, PPARG constitutive coactivator 1, Protein FAM120B