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Histone 3 Antikörper (H3K27me3) (AbBy Fluor® 680)

Dieses Anti-Histone 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Histone 3 in WB und FACS. Geeignet für Human und Maus.
Produktnummer ABIN5004707

Kurzübersicht für Histone 3 Antikörper (H3K27me3) (AbBy Fluor® 680) (ABIN5004707)

Target

Alle Histone 3 (H3) Antikörper anzeigen
Histone 3 (H3) (Histone H3 (H3))

Reaktivität

  • 1352
  • 909
  • 812
  • 41
  • 39
  • 39
  • 34
  • 34
  • 26
  • 23
  • 21
  • 21
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 1156
  • 255
  • 12
  • 5
Kaninchen

Klonalität

  • 1074
  • 353
  • 1
Polyklonal

Konjugat

  • 817
  • 72
  • 47
  • 46
  • 44
  • 44
  • 44
  • 44
  • 29
  • 27
  • 18
  • 18
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 7
  • 1
Dieser Histone 3 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation

  • 1028
  • 418
  • 374
  • 323
  • 253
  • 202
  • 188
  • 187
  • 163
  • 163
  • 148
  • 127
  • 115
  • 58
  • 48
  • 48
  • 35
  • 22
  • 16
  • 14
  • 7
  • 7
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 56
    • 50
    • 48
    • 43
    • 43
    • 37
    • 37
    • 36
    • 35
    • 35
    • 34
    • 33
    • 32
    • 31
    • 31
    • 30
    • 23
    • 23
    • 23
    • 22
    • 22
    • 19
    • 18
    • 17
    • 17
    • 17
    • 16
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    • 15
    • 15
    • 14
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 12
    • 11
    • 11
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    H3K27me3

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat,Dog,Cow,Sheep,Pig,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic methyl peptide derived from human Histone H3 around methylation site of Lys27

    Isotyp

    IgG
  • Applikationshinweise

    FCM 1:20-100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Andere Bezeichnung

    Histone H3

    Hintergrund

    Synonyms: Histone H3, H3 histone family member E pseudogene, H3F3, HIST3H3, Histone H3 3 pseudogene.

    Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

    Gen-ID

    3020
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