HHV DNA Polymerase Catalytic Subunit (AA 1131-1235) Antikörper (AbBy Fluor® 680)
Kurzübersicht für HHV DNA Polymerase Catalytic Subunit (AA 1131-1235) Antikörper (AbBy Fluor® 680) (ABIN5004603)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1131-1235
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Spezifität
- This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit
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Kreuzreaktivität
- Virus
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Kreuzreaktivität (Details)
- HHV1
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- HHV DNA Polymerase Catalytic Subunit
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Substanzklasse
- Viral Protein
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Hintergrund
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Synonyms: DPOL_HHV11, DNA polymerase catalytic subunit, UL30, HHV1gp046.
Background: Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.
Target
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