HDAC8 Antikörper (AA 151-250) (AbBy Fluor® 750)
Kurzübersicht für HDAC8 Antikörper (AA 151-250) (AbBy Fluor® 750) (ABIN5004364)
Target
Alle HDAC8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 151-250
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Cow,Pig,Horse,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human HDAC8
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- HDAC8 (Histone Deacetylase 8 (HDAC8))
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Andere Bezeichnung
- HDAC8
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Hintergrund
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Synonyms: HD8, WTS, RPD3, CDA07, CDLS5, MRXS6, HDACL1, Histone deacetylase 8, HDAC8
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
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Gen-ID
- 55869
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UniProt
- Q9BY41
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Pathways
- Cellular Glucan Metabolic Process
Target
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