GSX1/GSH1 Antikörper (AA 165-264) (AbBy Fluor® 680)

Produktnummer ABIN5004094

Der Kaninchen Polyklonal Anti-GSX1/GSH1-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, GSX1/GSH1 in Proben von Maus zu detektieren.

Kurzübersicht für GSX1/GSH1 Antikörper (AA 165-264) (AbBy Fluor® 680) (ABIN5004094)

Target: GSX1/GSH1 (GSX1) (GS Homeobox 1 (GSX1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSX1/GSH1 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GSX1/GSH1 Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 165-264

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Gsh1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GSX1/GSH1

Target: GSX1/GSH1 (GSX1) (GS Homeobox 1 (GSX1))

Andere Bezeichnung: Gsh1

Hintergrund:

Synonyms: GS homeo box protein 1, GS homeobox 1, GSH1, GSX1, GSX1_HUMAN, Homeobox protein GSH-1 , Homeobox protein Gsh1.

Background: Growth hormone-releasing hormone (GHRH) stimulates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene.