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Occludin Antikörper (C-Term)

Dieses Anti-Occludin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Occludin in WB, IF, IHC (p) und EIA. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN500409

Kurzübersicht für Occludin Antikörper (C-Term) (ABIN500409)

Target

Alle Occludin (OCLN) Antikörper anzeigen
Occludin (OCLN)

Reaktivität

  • 107
  • 64
  • 44
  • 34
  • 18
  • 13
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
Human, Maus, Ratte

Wirt

  • 95
  • 20
  • 3
  • 1
Kaninchen

Klonalität

  • 89
  • 30
Polyklonal

Konjugat

  • 60
  • 9
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser Occludin Antikörper ist unkonjugiert

Applikation

  • 96
  • 37
  • 32
  • 27
  • 26
  • 26
  • 20
  • 17
  • 15
  • 12
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 16
    • 16
    • 10
    • 9
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody detectc OCLN.

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    OCLN antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human OCLN.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Liang, Zhang, Deng, He, Liang, Liang, Chen, Tang, Chen, Yang: "The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 5378961, (2018) (PubMed).

    Zhang, Tang, Deng, Chen, Liang, Xie, He, Chen, Yang: "Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats." in: Biomedicine & pharmacotherapy, Vol. 102, pp. 1025-1036, (2018) (PubMed).

  • Target

    Occludin (OCLN)

    Andere Bezeichnung

    Occludin

    Hintergrund

    Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.Synonyms: OCLN

    Gen-ID

    4950

    UniProt

    Q16625

    Pathways

    Cell-Cell Junction Organization, Hepatitis C
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