Occludin Antikörper (C-Term)
Kurzübersicht für Occludin Antikörper (C-Term) (ABIN500409)
Target
Alle Occludin (OCLN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody detectc OCLN.
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Aufreinigung
- Peptide affinity chromatography
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Immunogen
- OCLN antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human OCLN.
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Isotyp
- IgG
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Applikationshinweise
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 5378961, (2018) (PubMed).
: "Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats." in: Biomedicine & pharmacotherapy, Vol. 102, pp. 1025-1036, (2018) (PubMed).
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The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 5378961, (2018) (PubMed).
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- Occludin (OCLN)
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Andere Bezeichnung
- Occludin
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Hintergrund
- Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.Synonyms: OCLN
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Gen-ID
- 4950
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UniProt
- Q16625
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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