NUP155 Antikörper (C-Term)

Produktnummer ABIN500397

Dieses Anti-NUP155-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NUP155 in WB und EIA. Geeignet für Human und Maus.

Kurzübersicht für NUP155 Antikörper (C-Term) (ABIN500397)

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP155 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-NUP155 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects NUP155 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatography

Immunogen: NUP155 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human NUP155.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu NUP155

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Andere Bezeichnung: NUP155

Hintergrund: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP)-155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.Synonyms: 155 kDa nucleoporin, KIAA0791, Nuclear pore complex protein Nup155, Nucleoporin Nup155

Gen-ID: 9631

NCBI Accession: NP_705618

UniProt: O75694

Pathways: Protein targeting to Nucleus