NPTX2 Antikörper (Center)

Produktnummer ABIN500385

Dieses Anti-NPTX2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NPTX2 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für NPTX2 Antikörper (Center) (ABIN500385)

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPTX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-NPTX2 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody is predicted to be specific to NPTX2 and not recognize NPTX1.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: NPTX2 antibody was raised against a 16 amino acid peptide near the center of the human NPTX2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu NPTX2

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Andere Bezeichnung: Neuronal Pentraxin-2

Hintergrund: Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson's disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD.Synonyms: NP2, NPTX2

Gen-ID: 4885

NCBI Accession: NP_002514

UniProt: P47972