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GLRB Antikörper (AA 51-150)

Der Kaninchen Polyklonal Anti-GLRB-Antikörper wurde für WB, ELISA, IF (cc), IF (p), ICC, IHC (fro) und IHC (p) validiert. Er ist geeignet, GLRB in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN5003557

Kurzübersicht für GLRB Antikörper (AA 51-150) (ABIN5003557)

Target

Alle GLRB Antikörper anzeigen
GLRB (Glycine Receptor, beta (GLRB))

Reaktivität

  • 34
  • 27
  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 40
  • 1
Kaninchen

Klonalität

  • 40
  • 1
Polyklonal

Konjugat

  • 13
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GLRB Antikörper ist unkonjugiert

Applikation

  • 30
  • 16
  • 12
  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Dog,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GLRB

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    GLRB (Glycine Receptor, beta (GLRB))

    Andere Bezeichnung

    GLRB

    Hintergrund

    Synonyms: Glycine receptor subunit beta, GLRB, Glycine receptor 58 kDa subunit

    Background: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

    Gen-ID

    2743

    UniProt

    P48167
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