GBAS Antikörper (N-Term)

Produktnummer ABIN500353

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GBAS in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für GBAS Antikörper (N-Term) (ABIN500353)

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-GBAS Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects NIPSNAP2 / GBAS at N-term. It is predicted to not cross-react with any other members of the NIPSNAP protein family.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: NIPSNAP2 antibody was raised against a 14 amino acid peptide near the amino terminus of human NIPSNAP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu GBAS

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Andere Bezeichnung: NIPSNAP2 / GBAS

Hintergrund: The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport.Synonyms: Protein NipSnap homolog 2, glioblastoma amplified sequence

Gen-ID: 2631

UniProt: O75323

Pathways: Ribonucleoside Biosynthetic Process