GK2 Antikörper (AA 101-200) (AbBy Fluor® 680)

Produktnummer ABIN5003515

Der Kaninchen Polyklonal Anti-GK2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, GK2 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für GK2 Antikörper (AA 101-200) (AbBy Fluor® 680) (ABIN5003515)

Target: GK2 (Glycerol Kinase 2 (GK2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GK2 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GK2 Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GK2/Glycerol kinase 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GK2

Target: GK2 (Glycerol Kinase 2 (GK2))

Andere Bezeichnung: GK2/Glycerol kinase 2

Hintergrund:

Synonyms: ATP:glycerol 3 phosphotransferase, EC 2.7.1.30, GK 2, GK, GKP2, GKTA, Glycerokinase, Glycerol kinase 2, Glycerol kinase testis specic 2, GLPK2_HUMAN.

Background: GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Gen-ID: 2712