NIPSNAP1 Antikörper (Center)
Kurzübersicht für NIPSNAP1 Antikörper (Center) (ABIN500351)
Target
Alle NIPSNAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Spezifität
- This antibody detects NipSnap1 at center.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
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Aufreinigung
- Peptide affinity chromatography
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Immunogen
- NIPSNAP antibody was raised against a 19 amino acid peptide from near the center of human NIPSNAP.
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Isotyp
- IgG
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Applikationshinweise
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- NIPSNAP1 (4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (NIPSNAP1))
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Andere Bezeichnung
- NipSnap1
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Hintergrund
- NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.Synonyms: Protein NipSnap homolog 1
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Gen-ID
- 8508
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NCBI Accession
- NP_003625
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UniProt
- Q9BPW8
Target
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