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METTL7B Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch METTL7B in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN500278

Kurzübersicht für METTL7B Antikörper (N-Term) (ABIN500278)

Target

Alle METTL7B Antikörper anzeigen
METTL7B (Methyltransferase Like 7B (METTL7B))

Reaktivität

  • 15
  • 14
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 15
Kaninchen

Klonalität

  • 15
Polyklonal

Konjugat

  • 10
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser METTL7B Antikörper ist unkonjugiert

Applikation

  • 14
  • 8
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    This antibody detects METTL7B at N-term.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, mouse

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    MettL7B antibody was raised against a 13 amino acid peptide near the amino terminus of human MettL7B.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target

    METTL7B (Methyltransferase Like 7B (METTL7B))

    Andere Bezeichnung

    METTL7B

    Hintergrund

    MettL7b belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.Synonyms: Methyltransferase-like protein 7B, UNQ594/PRO1180

    Gen-ID

    196410

    NCBI Accession

    NP_689850

    UniProt

    Q6UX53
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