FMR1 Antikörper (AA 20-48)

Produktnummer ABIN5002774

Der Maus Monoklonal anti-FMR1 Antikörper wird verwendet zum Nachweis von FMR1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für FMR1 Antikörper (AA 20-48) (ABIN5002774)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 8C2

Produktdetails anti-FMR1 Antikörper

Bindungsspezifität: AA 20-48

Verwendungszweck: FMR1 (8C2) Monoclonal Antibody

Kreuzreaktivität: Human

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin, Sodium azide

Vorsichtsmaßnahmen: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: FMR1

Hintergrund:

Synonyms: POF, FMRP, POF1, FRAXA, Synaptic functional regulator FMR1, Fragile X mental retardation protein 1, Protein FMR-1, FMR1

Background: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Gen-ID: 2332

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development