MATN1 Antikörper (N-Term)

Produktnummer ABIN500240

Der Kaninchen Polyklonal Anti-MATN1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, MATN1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für MATN1 Antikörper (N-Term) (ABIN500240)

Target: MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MATN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MATN1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects MATN1 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: MATN1 antibody was raised against a 12 amino acid peptide from near the amino terminus of human MATN1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu MATN1

Target: MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))

Andere Bezeichnung: Matrilin-1

Hintergrund: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.Synonyms: CMP, CRTM, Cartilage matrix protein, MATN1

Gen-ID: 4146

NCBI Accession: NP_002370

UniProt: P21941