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MARVELD1 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MARVELD1 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN500236

Kurzübersicht für MARVELD1 Antikörper (N-Term) (ABIN500236)

Target

Alle MARVELD1 Antikörper anzeigen
MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Reaktivität

Human, Maus, Ratte

Wirt

  • 10
  • 2
Kaninchen

Klonalität

  • 12
Polyklonal

Konjugat

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MARVELD1 Antikörper ist unkonjugiert

Applikation

  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 2
    • 1
    • 1
    N-Term

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, mouse, rat

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    MARVELD1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human MARVELD1.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store the antibody (in aliquots) at -20 °C.
  • Target

    MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

    Andere Bezeichnung

    MARVELD1

    Hintergrund

    MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression (1,3), suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.Synonyms: MARVEL domain-containing protein 1, MRVLDC1

    Gen-ID

    83742

    UniProt

    Q9BSK0
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