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MOAP1 Antikörper (Center)

MOAP1 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500228
  • Target Alle MOAP1 Antikörper anzeigen
    MOAP1 (Modulator of Apoptosis 1 (MOAP1))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 25
    • 4
    • 2
    Human, Maus
    Wirt
    • 22
    • 5
    Kaninchen
    Klonalität
    • 24
    • 3
    Polyklonal
    Konjugat
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MOAP1 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 16
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Modulator of apoptosis 1 at enter.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    MAP-1 antibody was raised against a 15 amino acid peptide from near the center of human MAP-1.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    MOAP1 (Modulator of Apoptosis 1 (MOAP1))
    Andere Bezeichnung
    MOAP1 (MOAP1 Produkte)
    Synonyme
    MOAP1 antikoerper, MAP-1 antikoerper, PNMA4 antikoerper, AA987038 antikoerper, Map-1 antikoerper, Pnma4 antikoerper, modulator of apoptosis 1 antikoerper, modulator of apoptosis 1 S homeolog antikoerper, MOAP1 antikoerper, moap1.S antikoerper, Moap1 antikoerper
    Hintergrund
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains (reviewed in 2 and 3). A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo (4). It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis (5).Synonyms: MAP-1, MAP1, Modulator of apoptosis 1
    Gen-ID
    64112
    NCBI Accession
    NP_071434
    UniProt
    Q96BY2
    Pathways
    Positive Regulation of Endopeptidase Activity
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