MAK10/NAA35 Antikörper (N-Term)

Produktnummer ABIN500220

Dieses Anti-MAK10/NAA35-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MAK10/NAA35 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MAK10/NAA35 Antikörper (N-Term) (ABIN500220)

Target: MAK10/NAA35 (MAK10) (MAK10 Homolog, Amino-Acid N-Acetyltransferase Subunit (MAK10))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAK10/NAA35 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-MAK10/NAA35 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects MAK10 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: 19 amino acid peptide near the amino terminus of human MAK10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu MAK10/NAA35

Target: MAK10/NAA35 (MAK10) (MAK10 Homolog, Amino-Acid N-Acetyltransferase Subunit (MAK10))

Andere Bezeichnung: NAA35 / MAK10

Hintergrund: The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.Synonyms: EGAP, Embryonic growth-associated protein homolog, N-alpha-acetyltransferase 35 NatC auxiliary subunit

Gen-ID: 60560

NCBI Accession: NP_078911

UniProt: Q5VZE5