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MAEL Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAEL in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN500218

Kurzübersicht für MAEL Antikörper (C-Term) (ABIN500218)

Target

Alle MAEL Antikörper anzeigen
MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reaktivität

Human, Maus, Ratte

Wirt

  • 8
Kaninchen

Klonalität

  • 8
Polyklonal

Konjugat

  • 4
  • 2
  • 1
  • 1
Dieser MAEL Antikörper ist unkonjugiert

Applikation

  • 7
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 5
    • 2
    • 1
    • 1
    C-Term

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, mouse, rat

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    Maelstrom antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Maelstrom.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store the antibody (in aliquots) at -20 °C.
  • Target

    MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

    Andere Bezeichnung

    MAEL

    Hintergrund

    The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.Synonyms: Protein maelstrom homolog

    Gen-ID

    84944

    UniProt

    Q96JY0
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