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SCARB2 Antikörper (Center)

Dieses Anti-SCARB2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SCARB2 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN500172

Kurzübersicht für SCARB2 Antikörper (Center) (ABIN500172)

Target

Alle SCARB2 Antikörper anzeigen
SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reaktivität

  • 48
  • 32
  • 13
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 43
  • 4
  • 2
  • 1
Kaninchen

Klonalität

  • 45
  • 5
Polyklonal

Konjugat

  • 24
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SCARB2 Antikörper ist unkonjugiert

Applikation

  • 38
  • 17
  • 13
  • 13
  • 11
  • 9
  • 6
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Spezifität

    This antibody detects SCARB2

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, mouse, rat

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    LIMP2 antibody was raised against a 16 amino acid peptide from near the center of human LIMP2.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target

    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

    Andere Bezeichnung

    SCARB2

    Hintergrund

    The lysosomal integral membrane protein 2 (LIMP2) is a heavily glycosylated type III transmembrane protein, the majority of which exists in the lumen of the lysosome and a cytoplasmic domain of approximately 20 amino acids. A deficiency of LIMP2 in mice causes uretic pelvic junction obstruction, deafness, and peripheral neuropathy associated with impaired vesicular trafficking and distribution of apically expressed proteins. More recently, LIMP2 was shown to act as a receptor to bind b-glucocerebrosidase, the enzyme defective in Gaucher disease, a lysosomal storage disorder. LIMP2-deficient mice showed missorted as well as secreted b-glucocerebrosidase, suggesting that LIMP2 also functions as the mannose-6-phosphate-independent trafficking receptor. Despite its predicted molecular weight, LIMP2 runs at approximately 80 - 85 kDa in SDS-PAGE.Synonyms: 85 kDa lysosomal membrane sialoglycoprotein, CD36 antigen-like 2, CD36L2, LGP85, LIMP II, LIMP2, LIMPII, Lysosome membrane protein 2, SR-BII, SRB2, Scavenger receptor class B member 2

    Gen-ID

    950

    UniProt

    Q14108
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