DHX58 Antikörper (C-Term)

Produktnummer ABIN500164

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DHX58 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für DHX58 Antikörper (C-Term) (ABIN500164)

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX58 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-DHX58 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects DHX58 at C-term.

Aufreinigung: Peptide affinity chromatography

Immunogen: LGP2 antibody was raised against a 12 amino acid peptide from near the carboxy terminus of human LGP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DHX58

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Andere Bezeichnung: DHX58

Hintergrund: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.Synonyms: ATP-dependent RNA helicase DHX58, ATP-dependent helicase LGP2, D11LGP2E, DHX58, LGP2, Protein D11Lgp2 homolog

Gen-ID: 79132

UniProt: Q96C10