LGI2 Antikörper (Center)

Produktnummer ABIN500156

Der Kaninchen Polyklonal anti-LGI2 Antikörper wird verwendet zum Nachweis von LGI2 in Proben von Human und Maus. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für LGI2 Antikörper (Center) (ABIN500156)

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-LGI2 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody detetcs LGI2 at center. It will recognize only the longest isoform. The antibody is predicted to be specific to LGI2 and not recognize other LGI proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatography

Immunogen: LGI2 antibody was raised against a 10 amino acid peptide from near the center of human LGI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu LGI2

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Andere Bezeichnung: LGI2

Hintergrund: The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE. Three isoforms of LGI2 are known to exist.Synonyms: KIAA1916, LGI1-like protein 2, LGI2, LGIL2, Leucine-rich glioma-inactivated protein 2, Leucine-rich repeat LGI family member 2

Gen-ID: 55203

NCBI Accession: NP_060646

UniProt: Q8N0V4