LGI2 Antikörper (N-Term)

Produktnummer ABIN500154

Produktdetails anti-LGI2 Antikörper

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects LGI2 at N-term (only the longest isoform). It is predicted to be specific to LGI2 and not recognize other LGI proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: LGI2 antibody was raised against a 11 amino acid peptide from near the amino terminus of human LGI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu LGI2

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Andere Bezeichnung: LGI2 (LGI2 Produkte)

Synonyme: LGIL2 antikoerper, mKIAA1916 antikoerper, leucine rich repeat LGI family member 2 antikoerper, leucine-rich repeat LGI family, member 2 antikoerper, leucine-rich repeat LGI family member 2 antikoerper, leucine-rich repeat LGI family, member 2a antikoerper, LGI2 antikoerper, Lgi2 antikoerper, lgi2 antikoerper, lgi2a antikoerper

Hintergrund: The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE. Three isoforms of LGI2 are known to exist.Synonyms: KIAA1916, LGI1-like protein 2, LGI2, LGIL2, Leucine-rich glioma-inactivated protein 2, Leucine-rich repeat LGI family member 2

Gen-ID: 55203

NCBI Accession: NP_060646

UniProt: Q8N0V4