FAIM2 Antikörper (N-Term)

Produktnummer ABIN500148

Dieses Anti-FAIM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FAIM2 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für FAIM2 Antikörper (N-Term) (ABIN500148)

Target: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-FAIM2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects FAIM2.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: LFG antibody was raised against a 16 amino acid peptide from near the amino terminus of human LFG.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu FAIM2

Target: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Andere Bezeichnung: FAIM2

Hintergrund: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. LFG is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-? death signal. In this respect, LFG is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. LFG, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. LFG is widely distributed, but highly expressed in the hippocampus and other neural tissues. LFG was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.Synonyms: Fas apoptotic inhibitory molecule 2, KIAA0950, LFG, Protein lifeguard, TMBIM2, Transmembrane BAX inhibitor motif-containing protein 2

Gen-ID: 23017

UniProt: Q9BWQ8