CERS6 Antikörper (N-Term)

Produktnummer ABIN500144

Der Kaninchen Polyklonal Anti-CERS6-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, CERS6 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CERS6 Antikörper (N-Term) (ABIN500144)

Target: CERS6 (Ceramide Synthase 6 (CERS6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CERS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CERS6 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects LASS6. It is predicted not to cross-react with LASS5.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: LASS6 antibody was raised against a 13 amino acid peptide near the amino terminus of the human LASS6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu CERS6

Target: CERS6 (Ceramide Synthase 6 (CERS6))

Andere Bezeichnung: LASS6

Hintergrund: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development. At least two isoforms of LASS6 are known to exist.Synonyms: LAG1 longevity assurance homolog 6

Gen-ID: 253782

NCBI Accession: NP_982288

UniProt: Q6ZMG9