LRRC1 Antikörper (C-Term)

Produktnummer ABIN500136

Dieses Anti-LRRC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LRRC1 in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für LRRC1 Antikörper (C-Term) (ABIN500136)

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-LRRC1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects LRRC1.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Peptide affinity chromatography

Immunogen: Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 -2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu LRRC1

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Andere Bezeichnung: LRRC1

Hintergrund: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble (1). The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells (2). Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions (1,3). It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues (4,5).Synonyms: LANO, LANO adapter protein, LAP and no PDZ protein, LRRC1, Leucine-rich repeat-containing protein 1

Gen-ID: 55227

UniProt: Q9BTT6