KLHL1 Antikörper (N-Term)

Produktnummer ABIN500126

Der Kaninchen Polyklonal Anti-KLHL1-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, KLHL1 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für KLHL1 Antikörper (N-Term) (ABIN500126)

Target: KLHL1 (Kelch-Like 1 (KLHL1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLHL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-KLHL1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects Kelch-like 1 protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: KLHL1 antibody was raised against a 14 amino acid peptide from near the amino-terminus of human KLHL1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 2 - 4 μg/mL. Human brain cell lysate can be used as positive control. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu KLHL1

Target: KLHL1 (Kelch-Like 1 (KLHL1))

Hintergrund: The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues (1,2). The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins (3). Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression (1).Synonyms: KIAA1490, KLHL1

Gen-ID: 57626

UniProt: Q9NR64