DGAT1 Antikörper (AA 251-350) (AbBy Fluor® 750)
Quick Overview for DGAT1 Antikörper (AA 251-350) (AbBy Fluor® 750) (ABIN5001213)
Target
Alle DGAT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 251-350
-
Kreuzreaktivität
- Hund, Human, Maus, Ratte
-
Homologie
- Pig,Horse
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human DGAT1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
-
Andere Bezeichnung
- DGAT1/Diglyceride acyltransferase
-
Hintergrund
-
Synonyms: ARAT, DGAT, ARGP1, DIAR7, Diacylglycerol O-acyltransferase 1, ACAT-related gene product 1, Acyl-CoA retinol O-fatty-acyltransferase, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase, DGAT1, AGRP1
Background: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
-
Gen-ID
- 8694
-
UniProt
- O75907
-
Pathways
- Hormone Transport
Target
-