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NKIRAS1 Antikörper (C-Term)

Dieses Anti-NKIRAS1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NKIRAS1 in WB, IF und EIA. Geeignet für Human und Maus.
Produktnummer ABIN500112

Kurzübersicht für NKIRAS1 Antikörper (C-Term) (ABIN500112)

Target

Alle NKIRAS1 Antikörper anzeigen
NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reaktivität

  • 32
  • 25
  • 21
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 40
  • 7
Kaninchen

Klonalität

  • 40
  • 7
Polyklonal

Konjugat

  • 24
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NKIRAS1 Antikörper ist unkonjugiert

Applikation

  • 43
  • 23
  • 13
  • 13
  • 8
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody is specific for kappaB-ras1 and has no cross-reactivity to kappaB-ras2.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, mouse

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    KappaB ras1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human KappaB ras1.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target

    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

    Andere Bezeichnung

    NKIRAS1

    Hintergrund

    KappaB ras-1 (kappaB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkappaB), an inhibitor of the transcription factor NF-kappaB. IkappaB exists in two homologous forms, IkappaB-alpha and IkappaB-beta, although IkappaB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkappaB-alpha-NF-kappaB complexes can shuttle in and out of the nucleus, IkappaB-beta-NF-kappaB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkappaB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkappaB-beta and regulating the rate of degradation of IkappaB-beta.Synonyms: KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1

    Gen-ID

    28512

    UniProt

    Q9NYS0
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