IL27 Antikörper (N-Term)

Produktnummer ABIN500000

Der Kaninchen Polyklonal anti-IL27 Antikörper wird verwendet zum Nachweis von IL27 in Proben von Human und Maus. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für IL27 Antikörper (N-Term) (ABIN500000)

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-IL27 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to IL-27.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Affinity chromatography purified via peptide column

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 2 - 4 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu IL27

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Andere Bezeichnung: Interleukin-27 / IL27A

Hintergrund: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-γ, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28

Gen-ID: 246778

NCBI Accession: NP_663634

UniProt: Q8NEV9