CENPK Antikörper (AA 51-150) (AbBy Fluor® 680)

Produktnummer ABIN4999903

Der Kaninchen Polyklonal Anti-CENPK-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, CENPK in Proben von Human zu detektieren.

Kurzübersicht für CENPK Antikörper (AA 51-150) (AbBy Fluor® 680) (ABIN4999903)

Target: CENPK (Centromere Protein K (CENPK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPK Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CENPK Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 51-150

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FKSG14/Centromere protein K

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CENPK

Target: CENPK (Centromere Protein K (CENPK))

Andere Bezeichnung: Centromere protein K

Hintergrund:

Synonyms: AF5 alpha, AF5alpha, B130045K24Rik, BB232189, C530004N04Rik, CENP K, CENPK, Centromere protein K, Centromeric protein K, FKSG 14, ICEN 37, ICEN37, Interphase centromere complex protein 37, Leucine zipper protein FKSG14, OTTHUMP00000161888, P33, Protein AF 5alpha, Protein AF5alpha, Solt, Solzt, SoxLZ/Sox6 binding protein Solt, SoxLZ/Sox6 leucine zipper binding protein, CENPK_HUMAN.

Background: FKSG14, also known as CENPK (centromere protein K) is a component of the CENPA-CAD (nucleosome distal) complex. It may be involved in incorporation of CENPA into centromeres and is required for proper kinetochore function, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore. FKSG14 constitutively localized to centromeres throughout the cell cycle. There are 3 isoforms produced by alternative splicing.

Gen-ID: 64105