Interleukin 17a Antikörper (N-Term)

Produktnummer ABIN499978

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Interleukin 17a in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Interleukin 17a Antikörper (N-Term) (ABIN499978)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Interleukin 17a Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to Il-17.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: IL-17 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-17A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: Interleukin-17A (IL17A)

Hintergrund: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-kB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17

Gen-ID: 3605

NCBI Accession: NP_002181

UniProt: Q16552